Kilosort4

Kilosort4 is a Python package for spike sorting on GPUs with template matching. The software uses new graph-based approaches to clustering that improve performance compared to previous versions. For detailed comparisons to past versions of Kilosort and to other spike-sorting methods, please see our pre-print on BioArxiv.

Getting Started

• README
• How to use the GUI
• When to adjust default settings
• Using probes with multiple shanks
• Hardware recommendations
• Drift correction

Tutorials

• Example spike-sorting analysis with sample data
• Creating a Kilosort4 probe dictionary
• Loading other data formats with SpikeInterface